Preclinical investigation and clinical experience have provided evidence on the potential anticancer effect of artemisinin and its derivatives in the recent two decades. The major mechanisms of action of artemisinin and its derivatives may be due to toxic-free radicals generated by an endoperoxide moiety, cell cycle arrest, induction of apoptosis, and inhibition of tumor angiogenesis. It is a very promising  a new class of antitumor drugs of wide spectrum due to their detailed information regarding efficacy and safety. Keywords: artemisinin, anticancer activity, repurposed, specific drug delivery system, clinical trials

Link https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6272993/

Artemisinin and Its Derivatives as a Repurposing Anticancer Agent: What Else Do We Need to Do?